A huge Indian contingent embarks on a dangerous cat-and-mouse trail of capturing DON (Shah Rukh Khan) - the ruthless drug mafia in Malaysia. When DON gets seriously injured in a police encounter, the word that he is dead begins to do the rounds. The reality, of course, is that DON is held captive in a secret location, while his bumpkin of a look-alike, Vijay, is polished and sent to take down DON’s gang. In a bizarre twist of fate, when the man shielding the humble and streetwise Vijay, is killed, the latter comes to terms with the horrifying realization that both the police and the gang are out to nab him for different reasons. In a desperate attempt to prove his innocence, he is aided by the glamorously staggering Roma (Priyanka Chopra), and handsomely striking, Jasjit (Arjun Rampal), who owes Vijay a favor for care-taking his son during his imprisonment. But will Vijay be successful in his mission? Based on the successful erstwhile classic of the same name, which featured the legendary Amitabh Bachchan, the contemporary and stylishly crafted DON, features Bollywood czar Shah Rukh Khan playing a double role in one of the most defining performances of his career, teamed for the first time with former Miss World, Priyanka Chopra.